1907
Jozsef Marek first publishes his observations of a paralytic disease affecting 4 cocks
Marek J (1907) Dtsch Tierärztl Wochenschr
15:417-421
The agent of Marek’s Disease is discovered to be a herpesvirus
Churchill AE, Biggs PM (1967) Nature 215:528-530
1969
First successful vaccine against a herpesviral disease and additonally, the first vaccine against a malignancy
Churchill AE, et al. (1969) Nature 221:744-747
The first isolation of Herpesvirus of turkeys
Kawamura H, et al. (1969) Avian Dis 13:853-863
1970
The biological source of cell-free, enveloped virions is demonstrated to be the feather follicle epithelium
Calnek BW, et al. (1970) Avian Dis 14:219-333
Herpesvirus of Turkeys is shown to function as a vaccine against Marek’s Disease
Okazaki W, et al. (1970) Avian Dis 14:413-429
1988
Genetic analysis of MDV and HVT lead to their reclassification as alphaherpesviruses
Buckmaster AD, et al. (1988) J Gen Virol 69:2033-2042
1991
First reported isolation of a recombinant Marek’s Disease Virus expressing a heterologous gene
Cantello J, et al. (1991) J Virol 65:1584-1588
1992
REV, an avian retrovirus integrates into MDV DNA; first report of retroviral integration into a herpesvirus
Isofort R, et al. (1992) Proc Natl Acad Sci 89(3) :991-995
